In this study guide, we review anemia, types of anemia, formulas, vocabulary, heme breakdown, and anemia of chronic diseases.
B-Cell Development Stages. stem cell –> early pro-B cell –> late pro-B cell –> large pre-B cell –> [1st checkpoint – selects for functional heavy chains] –> small pre-B cell –> [2nd checkpoint – select for functional light chains] –> Immature B cell (has surface IgM, no surface IgD). Somatic recombination is the process in which different individual gene segments of the H (heavy) chain combine with rearranged gene segments of the L (light) chain. The enzymes responsible for somatic recombination are the recombinase enzymes (RAG-1 and RAG-2) that recognize specific sequences (RSS) or recombination signal sequences. RAG-1 and RAG-2 are only expressed in B or T lymphocytes. These specific sequences recognized by the RAG-1 or RAG-2 enzymes are either a 1) heptamer or 2) nonamer. The heptamer literally contains 7 nucleotides, and the nonamer literally contains 9 nucleotides. There are typically 12 or 23 nucleotides in between the heptamer and nonamer to separate them.
In this quick and easy lesson, explore the histology of key reproductive system organs in females and males. Female Reproductive System: Histology and Organs. Male Reproductive System: Histology and Organs. Medicine. Medical School.
In this quick and easy guide, learn about Gastrointestinal System: Pathophysiology of Diseases and Cancers [Biology, MCAT, USMLE]. Topics include heptobiliary disease, understanding liver functions and cirrhosis, liver function tests, causes of liver injury, alcoholic hepatitis, NAFLD, NASH, viral hepatitis, autoimmune hepatitis, durg-induced liver injury, hereditary hemochromatosis, Wilson’s disease, Alpha-1 Antitrypsin Deficiency, PSC, PBC, cholelithiasis, cholecystitis, cholangitis, hepatocellular carcinoma, and more.
In this quick and easy lesson guide, learn about cell biology – the function and biogenesis of cellular membranes. Explain the metabolic and protein biosynthetic functions of the endoplasmic reticulum. Define key metabolic functions of the endoplasmic reticulum.
Illustrate the function of the endoplasmic reticulum in the cotranslational translocation of proteins made on membrane bound polysomes and their co- and post-translational modifications. Explain the function of the endoplasmic reticulum in protein folding and discuss the fate of misfolded proteins.
In this educational lesson, we learn about the purpose of gel electrophoresis and how gel electrophoresis works. Gel electrophoresis in a method of separating DNA. It can be used to separate the size of DNA, RNA, and protein. You first start with a variety of different fragments of DNA all mixed together. The gel is a porous matrix like a sponge and separates the DNA based on two main things: 1) size and 2) charge. The charge on DNA is what makes it move through the gel. DNA is a negatively charged molecule, so it will move towards a positive charge.
Chemical reactions happen around us all the time. These reactions occur when we cook or bake and even in our bodies, like when we breathe. Everyday objects are able to react and cause incredible reactions. Here are some easy science experiments you can create using things you can find around the house. Make sure you act safely during the experiment and have fun!
Digoxin is a drug that treats heart arrhythmias, left ventricular systolic dysfunction, and heart failure. In this succinct educational lesson, we learn about how digoxin works in treating heart arrhythmias and heart failure, digoxin toxicity and common side effects, and treatment for digoxin toxicity. We also have a mini quiz at the end, so you can test your knowledge on the pharmacology of digoxin.
Whether it’s a violin or a harmonica, learning to play an instrument takes time and effort to “perfect.” Musicians put hours and hours of hard work to perform in concerts, participate in competitions, or even just practice for fun at home. It can be frustrating to play the same piece hundreds and hundreds of times, especially if you still can’t get one section down. However, all of these hours of practicing actually do more than just putting on a perfect performance or impressing your family; playing an instrument can help your physical and mental state.
Rheumatoid arthritis is an autoimmune disease characterized by chronic inflammation in the joints of hands, feet, knees, etc. In this quick and easy lesson, we explain the standard medical treatment for patients with rheumatoid arthritis at the USMLE immunology level, including DMARDS (synthetics and biologics), NSAIDS, and glucocorticoids.
There are two types of chemoreceptors that help control and regulate our respiratory rate: 1) central chemoreceptors and 2) peripheral chemoreceptors. Both central chemoreceptors and peripheral chemoreceptors send signals to the main respiratory center in the brain that unconsciously tells our bodies to increase or reduce pulmonary ventilation. In this lesson, we describe the differences and similarities of central chemoreceptors and peripheral chemoreceptors for the pulmonary system.
From sour, sweet, and savory, cheese is a delicacy that connects people of all ages. It’s in hamburgers, pizza, salads, spaghetti, and desserts. Many of the world’s most popular dishes contain cheese, a food item that has been around humans for a long time. In this article, you will learn the incredible science that makes cheese possible. Although the exact origins of cheese are unknown, it is thought that cheese originated when humans first began domesticating milk-producing animals like cows and goats. In fact, there is a legend that the first person to discover cheese was a merchant who found his milk curdled inside his container made of a sheep’s stomach. To his surprise, the curdled milk had a unique flavor that quenched his hunger. Cheesemaking is also shown in the artwork of a number of ancient civilizations including the Roman Empire and Ancient Egypt. However, the cheeses that are popular today were not made until cheesemaking became widespread across European countries around 500 years ago and then came to America when Pilgrims brought cheesemaking techniques with them. Since then, the cheese industry boomed in America and as of 2017, Americans consumed an average of 37 pounds of cheese every year per person!
Native to New Guinea, bananas prefer tropical climates and can be grown year round. In terms of produce, the biggest distinction is between bananas and plantains, both of which belong to the same genus (Musa) and come in a range of cultivars, or varieties. Bananas are generally eaten raw or as part of a dessert or baked good. Plantains are a staple crop, culinary distinct due to their higher starch content, predisposing them to being cooked and fried as part of meals or snacks.
Biology Unit 5 Study Guide: Evolution. After his visit to the Galapagos Islands, Darwin came up with the theory of evolution. This theory stated that organisms change over time. The way that organisms change is through the process of natural selection. With examples, practice questions, and answers to help make evolution respiration easy to learn!
Moderate and extreme are relative terms. What many assume to be the normal conditions for life do not apply equally across all species. Habitability can be thought of in terms of the Goldilocks principle. For example, to survive people need an environment that is not too cold and not too hot. Ranges like this exist for other factors as well, such as pressure. However, what is just right for us and most other creatures can be too much or too little for some. Animals that live on the sea floor provide an illustrative example in this regard. Where people need submersibles to maintain their equilibria, creatures that natural selection has adapted to thrive in the ocean’s depths are right at home. Cold, highly pressurized environments are the norm for them. When deep sea creatures are brought to the surface through accident or scientific curiosity they often either melt, as with glacial ice worms, or fatally decompress, like with blobfish. In this way the term extremophile is a relative one and is used to describe organisms that live in environments that are extreme to us. Beyond their novelty, extremophiles are important objects of study as they challenge and expand our notions of life and its necessities.
Biology Unit 4 Study Guide: Genetics, Meiosis, DNA and Protein Synthesis. With examples and answers to help make meiosis, DNA replication, and RNA translation easy to learn!
To answer this question we will first have to review the physical properties of light and go over the basics of optics, which is the study of the relationship between sight and light. Visible light is a section of the electromagnetic spectrum, and it is the only portion that people can see. While electromagnetic radiation can be measured via its various prosperities, such as frequency or energy, it is most commonly categorized by wavelength. Taking one step back, radiation is the transfer of energy in the form of waves or particles. For electromagnetic radiation, wavelength is determined by measuring photons. Put simply, photons are massless particles that also exhibit the characteristics of waves. To measure wavelength a point is designated on one wave (usually a peak or trough) and the length between it and that same point on the next wave gives you the wavelength.
The overwhelming amount of commercials, advertisements, and promotional campaigns that Americans are bombarded with is astronomical, to the point it is affecting their dietary habits. As the turn from a nomadic lifestyle switched to one with steady food supplies and surplus, history of mankind derailed and took an entirely different course, one that would later involve corporations utilizing marketing communications to influence their consumers.
Hi Everyone! My friend just published a biology study guide book and it’s currently on sale! This book on biology study guides contains practice review questions and answers. Study Guides: Biology Unit Review Practice Questions and Answers . This interactive study guide of worksheets contains questions and answers to help you understand biology. Each unit contains information on key topics to review to further your understanding of biology. The units covered in this book include: ecology, biomolecules and cell biology, energy, photosynthesis, cellular respiration, cell division, mitosis, meiosis, protein synthesis, genetics, and evolution. Award-winning author and teacher Dr. Sam J. Alex created this study guide while inspired by students and teachers. All proceeds donated! Hope you find this book helpful on your journey into the wonderful world of biology and beyond!
Biology Unit 3 Study Guide: Cellular Processes – Photosynthesis and Cellular Respiration. Light Reactions and Calvin Cycle. Glycolysis, Krebs Cycle, and Electron Transport Chain. With examples and answers to help make photosynthesis and cellular respiration easy to learn!
Trees figure into the stories and symbols of religions across the world. In Norse mythology the ash tree Yggdrasil connects and supports the nine realms. Drawing from this and other traditions, various neopagan movements value, among other things, environmentalism for both secular and spiritual reasons. As for North America, trees and other plants are central to the Medicine practices of several tribes. The cedar tree even appears on the Medicine Wheel important to certain sacred rites, with the associated cardinal direction of the tree varying between different tribes. Cedar also figures into the religion of ancient Mesopotamia, forests of cedar being where their gods dwelled. That trees play a part in these and many other belief systems suggests that they have a fundamental appeal. In addition to being common components of many natural landscapes, trees are tall, sometimes imposing, and occasionally majestic. That people would attach and associate the reverence they feel toward religious subjects to these statuesque plants makes a lot of sense. In the past and up to the present, several religions have struck upon the same idea before encountering one another, the idea of a world tree. World trees are a type of axis mundi (world axis), a sort of pillar that conjoins or bridges the material and the spiritual. Yggdrasil is one example of this, and there are others as well. Beyond ashes and cedars, there are many other trees with sacred heritages. Notable among these are two varieties of fig.
Drugs for TB: What drugs treat tuberculosis TB? In this quick and easy lesson, we will explain the main drugs -rifamycin, isoniazid, pyrazinamide, ethambutol, and streptomycin – that treat Mycobacterium tuberculosis or TB and provide study aid mnemonics to aid in your USMLE learning.
Retroviruses are a class of viruses that not only infect host cells but also integrate their genetic material into the host genome, establishing a permanent infection that cannot be cured. The most common retrovirus is the human immunodeficiency virus or HIV, which targets and destroys helper T-cells.
Daydreaming is a common human phenomenon, one that we all experience in our daily lives. Studies show that we actually spend around 47% of our waking time in the dream world. We utilize this important tool to think-out different scenarios, re-visit special times in our lives, imagine new ones, or even just to pass time. Daydreaming is vital to the human experience. But one may wonder, what happens when one daydreams a little too much?
Sleep and Brain Activity Sleep disorders affect up to 70 million people and cost around $15.9 billion annually. EEG stands for electroencephalography, which was used to examine human brain waves in the 1950s. Sleep Disorders: Insomnia, OSA, Apnea, Narcolepsy. Regulation of Sleep. Sleep-Wakefulness Cycle: Circadium Rhythm and Homeostatic System. Tips to sleep better at night.