USMLE Protein-Energy Malnutrition diseases: Kwashiorkor vs Marasmus
KWASHIOrKOR vs MARASMUS
1. Causes of Kwashiorkor vs Marasmus
Daily, our body needs energy in the form of calories from food and water to function adequately. Our bodies also need certain amount of nutrients every day to function properly and maintain our health. Nutrients can come in the form of protein, carbohydrates, vitamins, and much more. When our bodies do not gain enough calories or nutrients, we may become undernourished or malnourished. Malnutrition is the main concept that is involved in both of these two diseases, Kwashiorkor and Marasmus for espeically young pediatric patients from impoverished and developing nations.

Kwashiorkor Causes: Malnutrition of protein; big emphasis on protein. Protein Malnutrition
Marasmus Causes: Malnutrition in general, including proteins, carbohydrates, fat, etc; Energy Malnutrition
Patients with Kwashiorkor are not getting enough protein in their energy intake and diet, while patients with Marasmus are not getting enough of food and energy in general, which can include proteins, fats, vitamins, carbohydrates, etc. Young children are especially vulnerable to food shortages, the main causes for these diseases.

2. symptoms of Kwashiorkor vs Marasmus


What are the differences in symptoms between the Kwashiorkor and Marasmus patients?
The symptoms of Kwashiorkor and Marasmus differ.
Kwashiorkor Symptoms: Symptoms of Kwashiorkor result from protein deficiency and are acute and rapid onset. Patients also are lethargic and sluggish. Use the mnemonic to remember the other main symptoms of Kwashiorkor: MEALS.
Mnemonic: Kwashiorkor = MEALS
- Malnutrition (protein deficiency specifically)
- Edema (large swollen protroding belly)
- Anemia
- Liver (enlarged and fatty, contributes to large belly)
- Skin lesions (Patients with Kwashiorkor have skin lesions including hyperkeratosis, which is excessive hardened skin, and dyspigmentation.)
Use the mnemonic MEALS to remember the symptoms of Kwashiorkor Disease, which will help differentiate from the Marasmus. 🙂
Marasmus Symptoms: Most prominent symptom is Muscle wasting, seen through ribs protruding. There is no visible large protroduing belly. Remember, patients with Marasmus are deficient in CALORIES not just protein. Patients are more irritable and active, unlike Kwashiorkor patients who are lethargic, unresponsive, and sluggish. Marasmus patients may also have diarrhea and dehydration.
Mnemonic: Marasmus = Muscle wasting

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Works Cited
- Dilated cardiomyopathy Induced by Chronic Starvation. https://www.researchgate.net/publication/310735913_Dilated_Cardiomyopathy_Induced_by_Chronic_Starvation_and_Selenium_Deficiency
- INCAP studies of kwashiorkor and marasmus. https://www.ncbi.nlm.nih.gov/pubmed/20461902
- Prenatal Factors Contribute to the Emergence of Kwashiorkor or Marasmus in Severe Undernutrition: Evidence for the Predictive Adaptation ModelDilated cardiomyopathy Induced by Chronic Starvation. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340401/
- First Aid USMLE Biochemistry 2019
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Just what I needed for my medical studies, thanks! Neat notes and easy to understand.
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Love your article! Very informative
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Thank you Mary R! So glad you liked our article! Happy studying! 🙂
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I learned something new from your article today. Thank you.
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Hi Percy, thank you for learning with us, and you’re very welcome!
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Reblogged this on ap5examtips.
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Another awesome post! Kwashiorkor is definitely a big problem in the world, glad to learn more about it.
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So glad you found this helpful, Mike!
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Lovely and beautifully written! I love reading your posts ❤️
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Thank you so much for your support, Athena!
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Reblogged this on nutrition101web.
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Informative and insightful! Thanks for the article
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😍thanks for the Article on kwashiorkor vs marasmus! Meals is a great mnemonic!
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You’re welcome Kayla. Glad to help. Good luck on your studies! 🙂
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