Category: immunology

Medical School: Learning about Wilson Disease – Pathophysiology, Symptoms, Diagnosis, and Treatment

What is Wilson disease? Do not fret, young medical student. In this lesson, we learn about Wilson disease and include high-yield medical school information, such as causes, pathology, diagnosis, and treatments. Test yourself with our high-yield question vignettes with answers on Wilson Disease.

Endocarditis vs Myocarditis vs Pericarditis – Causes, Symptoms, Diagnosis, Treatment, and Prognosis [MCAT, USMLE, Biology, Medicine]

Hello my lovely friends! And Happy Heart Month! In this lesson, we explore the circulatory system and share notes as part of the study guide series. We will continue to explore the awesome heart! Topics include inflammatory conditions of the heart: Endocarditis vs Myocarditis vs Pericarditis – Structure of the Layers of the Heart, Causes, Symptoms, Diagnosis, Treatment, and Prognosis.

Immunology 101: Stages of B-cell Development [Biology, MCAT, USMLE Medicine]

B-Cell Development Stages. stem cell –> early pro-B cell –> late pro-B cell –> large pre-B cell –> [1st checkpoint – selects for functional heavy chains] –> small pre-B cell –> [2nd checkpoint – select for functional light chains] –> Immature B cell (has surface IgM, no surface IgD). Somatic recombination is the process in which different individual gene segments of the H (heavy) chain combine with rearranged gene segments of the L (light) chain. The enzymes responsible for somatic recombination are the recombinase enzymes (RAG-1 and RAG-2) that recognize specific sequences (RSS) or recombination signal sequences. RAG-1 and RAG-2 are only expressed in B or T lymphocytes. These specific sequences recognized by the RAG-1 or RAG-2 enzymes are either a 1) heptamer or 2) nonamer. The heptamer literally contains 7 nucleotides, and the nonamer literally contains 9 nucleotides. There are typically 12 or 23 nucleotides in between the heptamer and nonamer to separate them.

Immunology: Treatments for Rheumatoid Arthritis – NSAIDs vs DMARDs vs Glucocorticoids [Biology, Medicine, MCAT, USMLE]

Rheumatoid arthritis is an autoimmune disease characterized by chronic inflammation in the joints of hands, feet, knees, etc. In this quick and easy lesson, we explain the standard medical treatment for patients with rheumatoid arthritis at the USMLE immunology level, including DMARDS (synthetics and biologics), NSAIDS, and glucocorticoids.

Biology Study Guide Book Just Published and on Sale! [Free Chapters]

Hi Everyone! My friend just published a biology study guide book and it’s currently on sale! This book on biology study guides contains practice review questions and answers. Study Guides: Biology Unit Review Practice Questions and Answers . This interactive study guide of worksheets contains questions and answers to help you understand biology. Each unit contains information on key topics to review to further your understanding of biology. The units covered in this book include: ecology, biomolecules and cell biology, energy, photosynthesis, cellular respiration, cell division, mitosis, meiosis, protein synthesis, genetics, and evolution. Award-winning author and teacher Dr. Sam J. Alex created this study guide while inspired by students and teachers. All proceeds donated! Hope you find this book helpful on your journey into the wonderful world of biology and beyond!

The Life Cycle of a Retrovirus: HIV

Retroviruses are a class of viruses that not only infect host cells but also integrate their genetic material into the host genome, establishing a permanent infection that cannot be cured. The most common retrovirus is the human immunodeficiency virus or HIV, which targets and destroys helper T-cells.

Vaccines 101: Vaccination, Immune System, and the COVID-19 Vaccine – Benefits and Side Effects

The question of how a vaccination would work to combat the current COVID-19 pandemic is a major concern right now. Everybody has their own perspective on the situation, and in some people’s minds, vaccines do not fit into the equation. Therefore, it’s extremely important to understand what a vaccine’s purpose is, how it is supposed to achieve that purpose, how a vaccine is developed, and its benefits versus side effects before coming to a final conclusion on the subject as it relates to the pandemic. To understand a vaccination’s purpose it is necessary to first understand how a pathogen works. A pathogen is essentially any foreign material (foreign in the sense that it is not a part of the human body), that can cause disease or a malfunction of the body. They spread from surface to surface and person to person.